John E. Starrett Jr. : rechercher sur Z-Library

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1

Application of the Heck reaction in the synthesis of truncated naphthoic acid retinoids

Kuo-Long Yu, Simon Chen, Jacek Ostrowski, Kenneth M. Tramposch, Peter R. Reczek, Muzammil M. Mansuri, John E. Starrett Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1996

Langue:

english

Fichier:

PDF, 286 KB

english, 1996

2

ChemInform Abstract: The Synthesis and Characterization of BMS-204352 (MaxiPost) and Related 3-Fluorooxindoles as Openers of Maxi-K Potassium Channels.

John E. Starrett Jr., et al. et al.

Journal:

Année:

2002

Fichier:

PDF, 31 KB

2002

3

ChemInform Abstract: The Synthesis and Structure—Activity Relationships of 1,3-Diaryl 1,2,4-(4H)-Triazol-5-ones: A New Class of Calcium-Dependent, Large Conductance, Potassium (Maxi-K) Channel Opener Targeted for Urge Urinary Incontinence.

Piyasena Hewawasam, Matthew Erway, George Thalody, Harvey Weiner, Christopher G. Boissard, Valentin K. Gribkoff, Nicholas A. Meanwell, Nicholas Lodge, John E. Starrett Jr.

Journal:

Année:

2002

Fichier:

PDF, 33 KB

2002

4

The Synthesis and Structure—Activity Relationships of 4-Aryl-3-aminoquinolin-2-ones: A New Class of Calcium-Dependent, Large Conductance, Potassium (Maxi-K) Channel Openers Targeted for Post-Stroke Neuroprotection.

Piyasena Hewawasam, Wenhong Fan, Jay Knipe, Sandra L. Moon, Christopher G. Boissard, Valentin K. Gribkoff, John E. Starrett Jr.

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 38 KB

english, 2002

5

Novel Openers of Ca2+-Dependent Large-Conductance Potassium Channels: Symmetrical Pharmacophore and Electrophysiological Evaluation of Bisphenols.

Yi Li, Graham Johnson, Jeffrey L. Romine, Nicholas A. Meanwell, Scott W. Martin, Steven I. Dworetzky, Christopher G. Boissard, Valentin K. Gribkoff, John E. Jr. Starrett

Journal:

Année:

2003

Fichier:

PDF, 70 KB

2003

6

Analogues (Ib)-(Ic) of a Potent Maxi-K Potassium Channel Opener (Ia) with an Improved Inhibitory Profile Toward Cytochrome P450 Isozymes.

Vivekananda M. Vrudhula, Bireshwar Dasgupta, Christopher G. Boissard, Valentin K. Gribkoff, Kenneth S. Santone, Richard A. Dalterio, Nicholas J. Lodge, John E. Jr. Starrett

Journal:

Année:

2005

Fichier:

PDF, 11 KB

2005

7

Synthesis of 3H and 14C labeled (S)-3-(5-chloro-2-methoxyphenyl)-1,3-dihydro-3-fluoro-6-(trifluoromethyl)-2H-indol-2-one, maxipost™. An agent for post-stroke neuroprotection

Douglas D. Dischino, Valentin K. Gribkoff, Piyasena Hewawasam, George M. Luke, J. Kent Rinehart, Tony L. Spears, John E. Starrett Jr

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

2003

Langue:

english

Fichier:

PDF, 113 KB

english, 2003

8

Microwave-assisted synthesis and chiral HPLC separation of 18F-labeled MaxiPost™. An agent for post-stroke neuroprotection

Douglas D. Dischino, Heidi A. Dulac, Kevin W. Gillman, Lynn S. Keller, Edward S. Kozlowski, Lawrence R. Marcin, James J. Mongillo, John E. Starrett Jr

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

2003

Langue:

english

Fichier:

PDF, 158 KB

english, 2003

9

Prodrugs of 2′,3′-didehydro-3′-deoxythymidine (D4T): Synthesis, antiviral activity, and rapid pharmacokinetic evaluation

David R. Tortolani, John W. Russell, Valerie J. Whiterock, Michael J. M. Hitchcock, Ismail Ghazzouli, John C. Martin, Muzammil M. Mansuri, John E. Starrett Jr.

Journal:

Journal of Pharmaceutical Sciences

Année:

1994

Langue:

english

Fichier:

PDF, 658 KB

english, 1994

10

A novel synthesis of 1, 2-diaryl-2, 2-difluoroethanones

Yu Kuo-Long, Mansuri M. Muzammil, Starrett E. John Jr.

Journal:

Tetrahedron Letters

Année:

1994

Langue:

english

Fichier:

PDF, 156 KB

english, 1994

11

Synthesis and KCNQ2 opener activity of N-(1-benzo[1,3]dioxol-5-yl-ethyl, N-[1-(2,3-dihydro-benzofuran-5-yl)-ethyl, and N-[1-(2,3-dihydro-1H-indol-5-yl)-ethyl acrylamides

Yong-Jin Wu, Li-Qiang Sun, Huan He, Jie Chen, John E Starrett Jr., Pierre Dextraze, Jean-Paul Daris, Christopher G Boissard, Rick L Pieschl, Valentin K Gribkoff, Joanne Natale, Ronald J Knox, David G

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 323 KB

english, 2004

12

3-Thio-quinolinone maxi-K openers for the treatment of erectile dysfunction

Kenneth M. Boy, Jason M. Guernon, Sing-Yuen Sit, Kai Xie, Piyasena Hewawasam, Christopher G. Boissard, Steven I. Dworetzky, Joanne Natale, Valentin K. Gribkoff, Nicholas Lodge, John E. Starrett Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 272 KB

english, 2004

13

Analogs of a potent maxi-K potassium channel opener with an improved inhibitory profile toward cytochrome P450 isozymes

Vivekananda M. Vrudhula, Bireshwar Dasgupta, Christopher G. Boissard, Valentin K. Gribkoff, Kenneth S. Santone, Richard A. Dalterio, Nicholas J. Lodge, John E. Starrett Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2005

Langue:

english

Fichier:

PDF, 187 KB

english, 2005

14

Preparation of the geometric isomers of DDC, DDA, D4C and D4T as potential anti-HIV agents

Muzammil M. Mansuri, Vittorio Farina, John E. Starrett Jr., Daniel A. Benigni, Vera Brankovan, John C. Martin

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1991

Langue:

english

Fichier:

PDF, 202 KB

english, 1991

15

The synthesis and structure–activity relationships of 1,3-diaryl 1,2,4-(4H)-triazol-5-ones: A new class of calcium-dependent, large conductance, potassium (maxi-k) channel opener targeted for urge urinary incontinence

Piyasena Hewawasam, Matthew Erway, George Thalody, Harvey Weiner, Christopher G Boissard, Valentin K Gribkoff, Nicholas A Meanwell, Nicholas Lodge, John E Starrett, Jr

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2002

Langue:

english

Fichier:

PDF, 109 KB

english, 2002

16

Structural modifications of 6-naphthalene-2-carboxylate retinoids

Kuo-Long Yu, Jacek Ostrowski, Simon Chen, Kenneth M. Tramposch, Peter R. Reczek, Muzammil M. Mansuri, John E. Starrett Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1996

Langue:

english

Fichier:

PDF, 325 KB

english, 1996

17

The synthesis and structure–activity relationships of 4-aryl-3-aminoquinolin-2-ones: a new class of calcium-Dependent, large conductance, potassium (maxi-K) channel openers targeted for post-stroke neuroprotection

Piyasena Hewawasam, Wenhong Fan, Jay Knipe, Sandra L Moon, Christopher G Boissard, Valentin K Gribkoff, John E Starrett Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2002

Langue:

english

Fichier:

PDF, 127 KB

english, 2002

18

Novel Openers of Ca2+-Dependent Large-Conductance Potassium Channels: Symmetrical Pharmacophore and Electrophysiological Evaluation of Bisphenols

Yi Li, Graham Johnson, Jeffrey L Romine, Nicholas A Meanwell, Scott W Martin, Steven I Dworetzky, Christopher G Boissard, Valentin K Gribkoff, John E Starrett Jr

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2003

Langue:

english

Fichier:

PDF, 128 KB

english, 2003

19

(S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzooxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability of rat hippocampal neurons

Yong-Jin Wu, Christopher G Boissard, Jie Chen, William Fitzpatrick, Qi Gao, Valentin K Gribkoff, David G Harden, Huan He, Ronald J Knox, Joanne Natale, Rick L Pieschl, John E Starrett Jr., Li-Qiang Su

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 230 KB

english, 2004

20

Radiochemical synthesis and biodistribution of a novel maxi-K potassium channel opener

Dale O Kiesewetter, Elaine M Jagoda, John E Starrett Jr, Valentin K Gribkoff, Piyasena Hewawasam, Nugahally Srinivas, Daniel Salazar, William C Eckelman

Journal:

Nuclear Medicine and Biology

Année:

2002

Langue:

english

Fichier:

PDF, 153 KB

english, 2002

21

Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine

John E. Starrett Jr., David R. Tortolani, Michael J.M. Hitchcock, John C. Martin, Muzammil M. Mansuri

Journal:

Antiviral Research

Année:

1992

Langue:

english

Fichier:

PDF, 367 KB

english, 1992

22

Structural studies of the anti-HIV agent 2′,3′-didehydro-2′,3′-dideoxythymidine (D4T)

William E. Harte Jr., John E. Starrett Jr., John C. Martin, Muzammil M. Mansuri

Journal:

Biochemical and Biophysical Research Communications

Année:

1991

Langue:

english

Fichier:

PDF, 329 KB

english, 1991

23

Synthesis, Oral Bioavailability Determination, and in vitro Evaluation of Prodrugs of the Antiviral Agent 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA)

Starrett, John E. Jr., Tortolani, David R., Russell, John, Hitchcock, Michael J. M., Whiterock, Valerie, Martin, John C., Mansuri, Muzammil M.

Journal:

Journal of Medicinal Chemistry

Année:

1994

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1994

24

Role of Retinoic Acid Receptor Gamma in the Rhino Mouse and Rabbit Irritation Models of Retinoid Activity

Reczek, Peter R., Ostrowski, Jacek, Yu, Kuo-Long, Chen, Simon, Hammer, Laura, Roalsvig, Thor, Starrett Jr., John E., Driscoll, Joyce Phelan, Whiting, Gary, Spinazze, Patrick G., Tramposch, Kenneth M.,

Journal:

Skin Pharmacology and Applied Skin Physiology

Année:

1995

Langue:

english

Fichier:

PDF, 1.28 MB

english, 1995